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KMID : 1013220080060020138
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Jouranl of the Korean Society of Clinical Toxicology
2008 Volume.6 No. 2 p.138 ~ p.141
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A case of Colchicine Intoxication Presenting as Acute Gastroenteritis
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Ahn Ji-Yun
Ahn Hee-Cheol
Son Yoo-Dong
Kwon-Hyuk Sool
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Abstract
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A 47-year-old woman ingested about 12 mg of colchicine with suicidal intent. Colchicine, a highly poisonous alkaloid, is a commonly used treatment for gout, Bechet’s disease, and familial Mediterranean fever. Despite the knowledge of its side effects, the risk of a significant overdose is under-appreciated. She suffered from acute multisystem toxicity, including gastrointestinal disorders, bone marrow suppression, alopecia, and probable pancreatitis, but she ultimately recovered with supportive therapy. We report a case of acute colchicine toxicity from a single overdose with a review of the literature.
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KEYWORD
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Colchicine, Poisoning, Gastroenteritis, Pancreatitis
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